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KMID : 0361019740170030061
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Korean Journal of Otolaryngology - Head and Neck Surgery
1974 Volume.17 No. 3 p.61 ~ p.68
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The Effect of Age in the Histopathological Changes of Distant Organs after Nasal Septal Stimulation
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高康勳/Park, Hye Ja
車日甫/申洪秀/Cha, Wal Bo/Shin, Hong Soo
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Abstract
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Over stimulation on the mucous membrane of the nasal septum was reported to bring histopat. .hological changes of vascular system of distant organs.
Author investigated the difference of these histopathological changes on the distant organs betw-eentwo groups, one was adult rabbits and the other Was young rabbits.
The stimuli given were submucosal injection to the nasal septum, with 0.85% saline and 0. 1% pilocarpine hydrochloride.
The result were obtained
1. More conspicious histopathological changes were seem at almost organ in adult rabbits.
2. There was no difference of histopathological changes according to different stimulating drugs in the lung.
3. There was no difference of histopathological changes according to different stimulating drugs in the kidney of young rabbits, but it was remarkable in changes in adult rabbits.
4. There were more remarkable histopathological changes in the liver of pilocarpine injected adult rabbits.
5. There were a little of changes in the adrenal gland and testis in all cases.
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